As near as I can tell, President Monson's
official Twitter account has never responded publicly to any tweet. I don't know if those who monitor his account would respond to a direct message; I rather doubt it, but you're welcome to try.
But as for your question about creating a video game or anime of the Book of Mormon, I see no reason why you couldn't simply choose to do it. The scriptures counsel us to "be anxiously engaged in a good cause, and do many things of [our] own free will" (
D&C 58:27). In the
2015 LDSTech App and Game Contest, dozens of developers created all sorts of apps, many of which had a Book of Mormon theme. If you have a good idea, you could certainly choose to create an app or video on your own (respecting the copyrights and other intellectual property rights of the Church, of course).
Questions that can benefit the larger community should be asked in a public forum, not a private message.